As we all know, sequencing Internet Explorer is not supported but you can sequence IE plugins and other settings required by web apps and simply create a shortcut pointing to the locally installed Internet Explorer.
Studio interprets the shortcut correctly. However, in earlier versions of 7.x, there’s an issue on the VDA with launching apps using the /appvve parameter. The end result you may see is that IE launches but puts your appvve argument into the URL and not launch within the App-V app. This may come as bad news but you will need 7.6 CU3 or later if you are LTSR or 7.8 or later.
If you have setup a new XenApp farm and it appears that your applications are launching from Storefront but fail to launch from the desktop with a “cannot start app” error, it may be due to your XML trust configuration setting.
Try: Set-BrokerSite -TrustRequestsSentToTheXmlServicePort $true from one of the Delivery Controllers with the Citrix Snapins added.This setting is required to trust the XML Service port when using SSON passthrough.
If you can’t publish applications from Citrix Studio successfully, you may need to look into your certificate.
If you have Transport type set to HTTPS (in Storefront under Manager Delivery Controllers, Edit Store\Site), try flipping it to HTTP. If that works it indicates you likely have an SSL issue. You need to have a valid certificate across all delivery controllers. You also need to configure the binding in IIS as per the article: https://support.citrix.com/article/CTX215807
It’s also possible that apps won’t appear if filters have been configured in your environment: https://www.citrix.com/blogs/2014/03/27/hiding-applications-in-citrix-storefront/
These articles were originally posted on http://www.rorymon.com/blog/